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Dihydromyricetin

Plant sources:Dihydromyricetin is a single flavonoid isolated and purified from Ampelopsis gross dentata, a plant of Ampelopsis in the Vitaceae family.
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[1] Xie J, Liu J, Chen TM, et al. Dihydromyricetin alleviates carbon tetrachloride-induced acute liver injury via JNK-dependent mechanism in mice[J]. World J Gastroenterol, 2015, 21(18): 5473-81.

[2] Zhang Z, Zhang H, Chen S, et al. Dihydromyricetin induces mitochondria-mediated apoptosis in HepG2 cells through down-regulation of the Akt/Bad pathway[J]. Nutr Res, 2017, 38: 27-33.

[3] Liu S, Liu Q, Peng Q, et al. [Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats]. Nan Fang Yi Ke Da Xue Xue Bao, 2022, 42(5): 641-648.

[4] Hou XL, Tong Q, Wang WQ, et al. Suppression of Inflammatory Responses by Dihydromyricetin, a Flavonoid from Ampelopsis grossedentata, via Inhibiting the Activation of NF-κB and MAPK Signaling Pathways[J]. J Nat Prod, 2015, 78(7): 1689-96.

[5] Luo JD, Wu D, Lyu HJ, et al. [Effects of dihydromyricetin on high fat diet induced obesity in mice and its mechanism]. Zhongguo Ying Yong Sheng Li Xue Za Zhi, 2020, 36(1): 6-11.

[6] Ren ZX, Zhao YF, Cao T, et al. Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity[J]. Acta Pharmacol Sin, 2016, 37(10): 1315-1324.

[7] Yang D, Yang Z, Chen L, et al. Dihydromyricetin increases endothelial nitric oxide production and inhibits atherosclerosis through microRNA-21 in apolipoprotein E-deficient mice[J]. J Cell Mol Med, 2020, 24(10): 5911-5925.