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Eriodictyol
Plant sources：Eriodictyol is a natural flavonoid mainly extracted from the fruit of Citrus limon in the Rutaceae family and the plant of Dracocephalum in the Lamiaceae family.
[1] Lv P, Yu J, Xu X, et al. Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells[J]. J Cell Biochem, 2019, 120(4): 5644-5651.
[2] Liu Y, Yan X. Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through AKT/FOXO1 signaling[J]. J Cell Biochem, 2019, 120(9): 14628-14635.
[3] He P, Yan S, Zheng J, et al. Eriodictyol Attenuates LPS-Induced Neuroinflammation, Amyloidogenesis, and Cognitive Impairments via the Inhibition of NF-κB in Male C57BL/6J Mice and BV2 Microglial Cells[J]. J Agric Food Chem, 2018, 66(39): 10205-10214.
[4] Hameed A, Hafizur RM, Hussain N, et al. Eriodictyol stimulates insulin secretion through cAMP/PKA signaling pathway in mice islets[J]. Eur J Pharmacol, 2018, 820: 245-255.
[5] Wang X, Chen J, Tie H, et al. Eriodictyol regulated ferroptosis, mitochondrial dysfunction, and cell viability via Nrf2/HO-1/NQO1 signaling pathway in ovarian cancer cells[J]. J Biochem Mol Toxicol, 2023, 37(7): e23368.
[6] Wang Z, Lan Y, Chen M, et al. Eriodictyol, Not Its Glucuronide Metabolites, Attenuates Acetaminophen-Induced Hepatotoxicity[J]. Mol Pharm, 2017, 14(9): 2937-2951.
